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House Price Crash Forum


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About Discopants

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  1. Weak pound would not only encourage Brits to holiday in the UK it would also mean cheaper holidays for foreigners here...... So yes buy buy buy Butlins
  2. First thread in a long time, friend of the wife has just been Gazumped on a new build by a local builder who's son she went to school with. Not only that but her parents too. Both have completed on selling their own properties and are all living at their soon to be sold parents house. Wife's friend went to school with the builder and he has basically strung both families along assuring them that he would let them complete at the agreed price until, (but letting them know he had had better offers a week before exchange. This will leave them all homeless shortly. It's pure greed, on the builders behalf.
  3. If you want to fast track your career, this is the only way to do it in my opinion, you get subjected to a lot of experience quickly, with training for every posting. If you are new to a position you naturally challenge the status quo at first, and can implement improvements. After a couple of years you are more likely to be systemised. Saying, that This is not the path I have taken having only worked for 2 companies in my career, but I have taken a number of roles in that time. I have 2 friends that are not outstandingly intelligent, that have done very well for themselves by moving around a lot.
  4. It's not necessarily a simple process to know what salt form or similarly co crystal is going to be your target when you start developing an Active Pharmaceutical Ingredient Issues effecting the choice are stability of the molecule, bioavailability and drug delivery method. If you are making an non injectable formulation, when you swallow the tablet you generally don't want extremely quick dissolution and high availability of the drug in your system but only for a short period of time. Many drugs only work in safe doses if you get a sustained therapeutic dose. There are cancer therapies in development that are designed to be targeted, so the drug travels around your body but is only released in controlled areas of the body. This is not an easy business and development is very costly. We have very good therapies that are cheap for a huge range of conditions now. Pharma companies need incentive to go for the serious illnesses where the total patient population is small. Otherwise we are not going to get the range of cancer treatments and other gene therapies we need.
  5. Plus students are getting a spanking on higher education fees. Got to make you think twice about your other expenditure.
  6. It's going to be another Mr Trebus type I imagine. My link
  7. Groucho did say this though on politics. "Politics is the art of looking for trouble, finding it everywhere, diagnosing it incorrectly and applying the wrong remedies." I think we have to say he got that one right
  8. Will they ( the US) end up going for a massive pacific compensation lawsuit against Tepco ala BP in the gulf I wonder ?
  9. http://www.goodwithmoney.co.uk/ I wonder if they are going to re-examine their marketing strategy ?
  10. http://m.youtube.com/#/watch?v=PVyS9JwtFoQ&desktop_uri=%2Fwatch%3Fv%3DPVyS9JwtFoQ Has to be this one surely ?
  11. This is possibly where Sibley works Hatch Batten
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